Similac Infant Formula with 2’-FL HMO is comparable to the U.S. version of Similac Pro-Advance. Similac Infant Formula with 2’-FL HMO and nucleotides helps support baby’s immune system. This product was manufactured in Ireland. Abbott Nutrition has worked with the FDA to import this product to help with supply chain shortages. Because every baby’s tummy is unique, it can be difficult to predict how each baby will tolerate a formula change. It’s always best to talk to your pediatrician before making formula changes.